Cognitive changes of older adults with an equivocal amyloid load
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09203-5
Abstract: BackgroundObservational and interventional studies addressing the link between amyloid (Aβ) burden and cognitive decline are increasing, but a clear definition of amyloid positivity is still lacking. This may represent a great stake for therapeutic studies… read more here.
Keywords: equivocal amyloid; amyloid load; equivocal participants; older adults ... See more keywords
Treatment by low-dose brain radiation therapy improves memory performances without changes of the amyloid load in the TgF344-AD rat model
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.03.008
Abstract: Alzheimer's disease (AD) is a neurodegenerative condition affecting memory performance. This pathology is characterized by intracerebral amyloid plaques and tau tangles coupled with neuroinflammation. During the last century, numerous therapeutic trials unfortunately failed highlighting the… read more here.
Keywords: low dose; treatment; amyloid load; pathology ... See more keywords
β-Amyloid Load on PET Along the Continuum of Dementia With Lewy Bodies.
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000207393
Abstract: BACKGROUND Amyloid-β plaques can co-occur with Lewy-related pathology in patients with dementia with Lewy bodies (DLB), but amyloid-β load at prodromal stages of DLB still needs to be elucidated. We investigated amyloid-β load on PET… read more here.
Keywords: dlb; lewy bodies; dlb continuum; continuum ... See more keywords