If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?
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DOI: 10.1371/journal.pbio.3001694
Abstract: Strong genetic evidence supports an imbalance between production and clearance of amyloid β-protein (Aβ) in people with Alzheimer disease (AD). Microglia that are potentially involved in alternative mechanisms are actually integral to the amyloid cascade.… read more here.
Keywords: amyloid therapies; alzheimer disease; amyloid drives; anti amyloid ... See more keywords