Articles with "amyloid transthyretin" as a keyword



Systemic embolism in amyloid transthyretin cardiomyopathy

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Published in 2022 at "European Journal of Heart Failure"

DOI: 10.1002/ejhf.2566

Abstract: Although systemic embolism is a potential complication in transthyretin amyloid cardiomyopathy (ATTR‐CM), data about its incidence and prevalence are scarce. We studied the incidence, prevalence and factors associated with embolic events in ATTR‐CM. Additionally, we… read more here.

Keywords: systemic embolism; amyloid transthyretin; embolism amyloid; embolism ... See more keywords

“Living with a question mark”: psychosocial experience of Portuguese young adults at risk for hereditary amyloid transthyretin amyloidosis with polyneuropathy

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Published in 2024 at "Journal of Community Genetics"

DOI: 10.1007/s12687-024-00717-8

Abstract: This study is the first to explore the psychosocial experience of young Portuguese adults at genetic risk for hereditary amyloid transthyretin amyloidosis with polyneuropathy (hATTR-PN). The work focuses on the developmental peculiarities of their experience… read more here.

Keywords: hereditary amyloid; risk hereditary; young adults; psychosocial experience ... See more keywords

Left ventricular hypertrophy, dilatation and ejection fractions predict ventricular tachycardia in amyloid transthyretin cardiomyopathy

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Published in 2023 at "Europace"

DOI: 10.1093/europace/euad122.274

Abstract: Abstract Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Pfizer Global Medical Grant Background Amyloid transthyretin cardiomyopathy (ATTR-CM) is a progressive infiltrative cardiomyopathy caused by extracellular deposition of amyloid fibrils. The disease… read more here.

Keywords: ventricular tachycardias; amyloid transthyretin; ventricular tachycardia; transthyretin cardiomyopathy ... See more keywords

Amyloid transthyretin cardiac amyloidosis with different manifestations, test findings and types

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Published in 2023 at "BMJ Case Reports"

DOI: 10.1136/bcr-2022-250972

Abstract: Amyloid transthyretin amyloidosis usually presents with cardiac amyloidosis manifestations, most commonly with a heart failure syndrome. The history and physical examination offer clues of other cardiac and extracardiac manifestations. Taking a detailed history is essential… read more here.

Keywords: different manifestations; cardiac amyloidosis; amyloidosis different; amyloid transthyretin ... See more keywords

Abstract Fri050: The Role of Macrophages in the Progression of Amyloid Transthyretin Cardiomyopathy

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Published in 2025 at "Circulation Research"

DOI: 10.1161/res.137.suppl_1.fri050

Abstract: Introduction: Amyloid Transthyretin Cardiomyopathy (ATTR-CM) is caused by the myocardial uptake of transthyretin (TTR), resulting in protein aggregation, cytotoxicity, and ultimately dysfunction. Methods to enhance degradation of deposited TTR is a critical unmet need. Macrophages… read more here.

Keywords: role; attr; ttr; histology ... See more keywords