Exploring amyloid oligomers with peptide model systems.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2021.05.004
Abstract: The assembly of amyloidogenic peptides and proteins, such as the β-amyloid peptide, α-synuclein, huntingtin, tau, and islet amyloid polypeptide, into amyloid fibrils and oligomers is directly linked to amyloid diseases, such as Alzheimer's, Parkinson's, and… read more here.
Keywords: peptide model; peptides proteins; model systems; amyloidogenic peptides ... See more keywords
Amyloidogenic Peptides: New Class of Antimicrobial Peptides with the Novel Mechanism of Activity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105463
Abstract: Antibiotic-resistant bacteria are recognized as one of the leading causes of death in the world. We proposed and successfully tested peptides with a new mechanism of antimicrobial action “protein silencing” based on directed co-aggregation. The… read more here.
Keywords: class antimicrobial; amyloidogenic peptides; antimicrobial peptides; new class ... See more keywords
Amyloidogenic Peptides in Human Neuro-Degenerative Diseases and in Microorganisms: A Sorrow Shared Is a Sorrow Halved?
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25040925
Abstract: The term “amyloid” refers to proteinaceous deposits of peptides that might be generated from larger precursor proteins e.g., by proteolysis. Common to these peptides is a stable cross-β dominated secondary structure which allows self-assembly, leading… read more here.
Keywords: degenerative diseases; neuro degenerative; human neuro; peptides human ... See more keywords