Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
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DOI: 10.1038/s41556-021-00760-4
Abstract: Cells respond to stress by blocking translation, rewiring metabolism and forming transient messenger ribonucleoprotein assemblies called stress granules (SGs). After stress release, re-establishing homeostasis and disassembling SGs requires ATP-consuming processes. However, the molecular mechanisms whereby… read more here.
Keywords: metabolism; atp production; stress; amyloids pyruvate ... See more keywords