Effect of AmyTrap, an amyloid-β binding drug, on Aβ induced mitochondrial dysfunction and tau phosphorylation in cultured neuroblastoma cells
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DOI: 10.1007/s11011-019-00520-2
Abstract: Alzheimer’s Disease (AD) is the most common cause of dementia, affecting 25 million people worldwide. Accumulation of Amyloid-β (Aβ) in the mitochondria has been shown to adversely affect key enzymes including pyruvate dehydrogenase (PDH), succinate… read more here.
Keywords: tau; dysfunction; effect; amytrap ... See more keywords