Compensatory anabolic signaling in the sarcopenia of experimental chronic arthritis
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DOI: 10.1038/s41598-017-06581-6
Abstract: Inflammatory activity in rheumatoid arthritis may alter the regulation of muscle mass leading to a secondary sarcopenia, commonly termed rheumatoid cachexia (RC). We characterized alterations to muscle structure and various pro-inflammatory, catabolic and regenerative markers… read more here.
Keywords: chronic arthritis; arthritis; signaling sarcopenia; sarcopenia experimental ... See more keywords
P070 The influence of Crohn’s disease-derived blood plasma upon anabolic signaling responses to leucine stimulation in skeletal muscle cells in vitro
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DOI: 10.1093/ecco-jcc/jjad212.0200
Abstract: Many Crohn’s Disease (CD) patients have low muscle mass and function (sarcopenia), yet the precise drivers of this pathophysiology are unclear. Positive muscle protein balance is driven by essential amino acids (EAA) that stimulate muscle… read more here.
Keywords: anabolic signaling; crohn disease; phosphorylation; muscle ... See more keywords
Cannabidiol Does Not Impair Anabolic Signaling Following Eccentric Contractions in Rats.
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DOI: 10.1123/ijsnem.2020-0270
Abstract: Cannabidiol (CBD) has proven clinical benefits in the treatment of seizures, inflammation, and pain. The recent legalization of CBD in many countries has caused increased interest in the drug as an over-the-counter treatment for athletes… read more here.
Keywords: cbd; vehicle; cannabidiol impair; impair anabolic ... See more keywords
Novel Essential Amino Acid Supplements Following Resistance Exercise Induce Aminoacidemia and Enhance Anabolic Signaling Irrespective of Age: A Proof-of-Concept Trial
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DOI: 10.3390/nu12072067
Abstract: We investigated the effects of ingesting a leucine-enriched essential amino acid (EAA) gel alone or combined with resistance exercise (RE) versus RE alone (control) on plasma aminoacidemia and intramyocellular anabolic signaling in healthy younger (28… read more here.
Keywords: essential amino; age; eaa; com ... See more keywords