Binding mechanism of anacardic acid, carnosol and garcinol with PCAF: A comprehensive study using molecular docking and molecular dynamics simulations and binding free energy analysis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30400
Abstract: The p300/CBP associated factor bromodomain (PCAF Brd) is emerged as one of the promising target proteins for different types of cancers. PCAF is one among the histone acetyltransferase enzymes which involved in the regulation of… read more here.
Keywords: garcinol; acid carnosol; energy; anacardic acid ... See more keywords
Differential lethal action of C17:2 and C17:0 anacardic acid derivatives in Trypanosoma cruzi - A mechanistic study.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104068
Abstract: The n-hexane extract from leaves of Schinus terebinthifolius (Anacardiaceae) induced 100% of death of trypomastigote forms of T. cruzi at 300 μg/mL and was subjected to a bioactivity-guided fractionation to afford a C17:2 derivative of anacardic… read more here.
Keywords: salicylic acid; c17; compound; acid ... See more keywords
Anacardic acid suppresses fibroblast‐like synoviocyte proliferation and invasion and ameliorates collagen‐induced arthritis in a mouse model
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.09.008
Abstract: Abstract Anacardic acid, which is abundant in nutshell of Anacardium occidentale, has multiple pharmacological activities. In this study, we examined the therapeutic potential of anacardic acid in treating rheumatoid arthritis (RA). We explored the effects… read more here.
Keywords: arthritis; acid; anacardic acid; proliferation invasion ... See more keywords
Effects of industrial cashew nut processing on anacardic acid content and allergen recognition by IgE.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.07.146
Abstract: Cashew nuts are important both nutritionally and industrially, but can also cause food allergies in some individuals. The present study aimed to assess the effect(s) of industrial processing on anacardic acids and allergens present in… read more here.
Keywords: cashew; cashew nut; acid content; processing anacardic ... See more keywords
Anacardic Acid Suppresses Adipogenesis Through Inhibition of the Hsp90/Akt Signaling Pathway in 3T3-L1 Preadipocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal food"
DOI: 10.1089/jmf.2020.4830
Abstract: Anacardic acid (AA), a major component of cashew nut shell liquid, has extensive bioactivities. However, little is known about its antiadipogenic properties or the mechanism that underpins them. The aim of this study was to… read more here.
Keywords: akt signaling; acid suppresses; suppresses adipogenesis; signaling pathway ... See more keywords
A New Liposomal Formulation of Hydrogenated Anacardic Acid to Improve Activities Against Cancer Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Communications"
DOI: 10.1177/1934578x221105696
Abstract: Anacardic acid (AA) is a natural active ingredient that accounts for 65% of the liquid extract from the shell of the cashew nut. Due to the stronger cytotoxic activity of hydrogenated AA (HAA) against NTERA-2… read more here.
Keywords: ntera; cancer stem; stem cells; anacardic acid ... See more keywords
Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-018-2139-3
Abstract: BackgroundPancreatic cancer is one of the leading causes of cancer related death and its incidence has risen steadily. Although anticancer drugs have been developed based on the new molecular findings, the drugs have produced unsatisfactory… read more here.
Keywords: chmp1a; pancreatic cancer; effect; acid ... See more keywords
Calcium anacardate as source of anacardic acid in laying Japanese quail diet.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220190410
Abstract: Anacardic acid is naturally found in various parts of the cashew tree (Anacardium occidentale L.) and marketed as calcium anacardate. This product has antibacterial, antifungal and antioxidant activity, and has been used in humans in… read more here.
Keywords: calcium; calcium anacardate; anacardic acid; laying japanese ... See more keywords
The Anti-Inflammatory Effects of Anacardic Acid on a TNF-α - Induced Human Saphenous Vein Endothelial Cell Culture Model.
Sign Up to like & getrecommendations! Published in 2019 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201020666191105154619
Abstract: BACKGROUND AND OBJECTIVE Coronary bypass operations are commonly performed for treatment of ischemic heart diseases. Coronary artery bypass surgery with autologous human saphenous vein maintains its importance as a commonly used therapy for advanced atherosclerosis.… read more here.
Keywords: vein; human saphenous; tnf induced; saphenous vein ... See more keywords
Exploring an interesting dual functionality of anacardic acid for efficient paclitaxel delivery in breast cancer therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Nanomedicine"
DOI: 10.2217/nnm-2018-0138
Abstract: AIM To explore the potential of paclitaxel (PTX)-loaded anacardic acid conjugated hydrophobized gelatin nanoparticles. MATERIALS & METHODS Nanoparticles prepared by nanoprecipitation technique were evaluated for various quality attributes (particle size, % entrapment efficiency) in vitro… read more here.
Keywords: interesting dual; approximately fold; delivery; exploring interesting ... See more keywords
Synthesis of a tyrosinase inhibitor by consecutive ethenolysis and cross-metathesis of crude cashew nutshell liquid
Sign Up to like & getrecommendations! Published in 2018 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.14.252
Abstract: A convenient and sustainable three-step synthesis of the tyrosinase inhibitor 2-hydroxy-6-tridecylbenzoic acid was developed that starts directly from the anacardic acid component of natural cashew nutshell liquid (CNSL). Natural CNSL contains 60–70% of anacardic acid… read more here.
Keywords: tyrosinase inhibitor; nutshell liquid; cross metathesis; synthesis tyrosinase ... See more keywords