Nonplatinum‐based therapy with Paclitaxel and Capecitabine for advanced squamous cell carcinomas of the anal canal: A population‐based Danish anal cancer group study
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DOI: 10.1002/cam4.3886
Abstract: First‐line platinum‐based therapy for advanced squamous cell carcinomas of the anal canal (SCCA) implies a risk of substantial side effects, and data on second‐line treatment options are limited. Paclitaxel and Capecitabine are a well‐known regimen… read more here.
Keywords: squamous cell; carcinomas anal; anal canal; based therapy ... See more keywords
Acute toxicity and patient‐reported outcomes in anal canal cancer: results of a pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Radiation Sciences"
DOI: 10.1002/jmrs.604
Abstract: Anal canal cancer (ACC) is uncommon. The gold standard of care is chemoradiotherapy treatment. However, this treatment is associated with considerable acute and late side effects. The aim of this pilot study was to evaluate… read more here.
Keywords: patient reported; toxicity patient; anal canal; acute toxicity ... See more keywords
Is Local Resection of Anal Canal Tumors Feasible with Transanal Endoscopic Surgery?
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DOI: 10.1007/s00268-019-05262-x
Abstract: Background An important drawback of local surgery for lesions in the anal canal is the difficulty of achieving en bloc full-thickness resections. The aim of this study is to evaluate TEM/TEO in lesions of this… read more here.
Keywords: 192 500; surgery local; tem teo; anal canal ... See more keywords
Sampling reflex: a relic from the past or a useful parameter for the future?
Sign Up to like & getrecommendations! Published in 2021 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-021-02442-7
Abstract: We read with interest the paper by Pucciani et al. “Sampling reflex: pathogenic role in functional defecation disorder” [1]. This paper attempts to shed new light on the pathophysiology of dyssynergic defecation using perfused stationary… read more here.
Keywords: anal sphincter; anal canal; sampling reflex; relaxation ... See more keywords
Management of locally advanced anal canal carcinoma with intensity-modulated radiotherapy and concurrent chemotherapy
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DOI: 10.1007/s12032-018-1197-1
Abstract: The best curative option for locally advanced (stages II–III) squamous-cell carcinomas of the anal canal (SCCAC) is concurrent chemo-radiotherapy delivering 36–45 Gy to the prophylactic planning target volume with an additional boost of 14–20 Gy to the… read more here.
Keywords: management locally; modulated radiotherapy; anal canal; intensity modulated ... See more keywords
A Phase II Study of Capecitabine/Oxaliplatin With Concurrent Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Anal Canal.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical colorectal cancer"
DOI: 10.1016/j.clcc.2019.06.003
Abstract: INTRODUCTION Squamous cell carcinoma of the anal canal (SCCA) presents a rising incidence in the United States. Standard of care for locally advanced disease is comprised of infusional 5-fluorouracil with mitomycin C or cisplatin concurrent… read more here.
Keywords: anal canal; locally advanced; cell carcinoma; capecitabine oxaliplatin ... See more keywords
Real-time histological imaging of a squamous cell carcinoma in situ in the anal canal using endocytoscopy.
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DOI: 10.1055/a-1655-8401
Abstract: Squamous cell carcinoma (SCC) of the anal canal is rarely diagnosed at an early stage [1]. Endocytoscopy provides ultrahigh magnification, thereby allowing the diagnostic evaluation of structural and nuclear atypia and of the vascular structures… read more here.
Keywords: cell carcinoma; squamous cell; anal canal; situ anal ... See more keywords
So Now My Patient Has Squamous Cell Cancer: Diagnosis, Staging, and Treatment of Squamous Cell Carcinoma of the Anal Canal and Anal Margin.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics in colon and rectal surgery"
DOI: 10.1055/s-0038-1668105
Abstract: Squamous cell carcinomas of the anal canal and the anal margin are rare malignancies that are increasing in incidence. Patients with these tumors often experience delayed treatment due to delay in diagnosis or misdiagnosis of… read more here.
Keywords: treatment; squamous cell; anal canal; cell ... See more keywords
A phase II study of concurrent chemoradiotherapy with 5-fluorouracil and mitomycin-C for squamous cell carcinoma of the anal canal (the JROSG 10–2 trial)
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrac069
Abstract: Abstract This study assessed the efficacy of chemoradiotherapy for squamous cell carcinoma of the anal canal (SCCAC). Patients with T1–4N0-3M0 SCCAC received chemoradiotherapy with 5-fluorouracil (5-FU, 800 mg/m2/day, 96-h infusion) and mitomycin-C (MMC, 10 mg/m2… read more here.
Keywords: cell carcinoma; year; anal canal; squamous cell ... See more keywords
A rare case report of anal canal adenocarcinoma
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DOI: 10.1097/md.0000000000027083
Abstract: Abstract Rationale: Anal canal adenocarcinoma is a kind of rare malignant tumor of the intestinal tract with a low incidence rate. Patient concerns: A 42-year-old man came to our department with anal tenderness accompanied by… read more here.
Keywords: rare case; anal canal; pathology; case report ... See more keywords
Goblet cell adenocarcinoma of the anal canal with perianal Paget disease: A rare case report with literature review
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DOI: 10.1097/md.0000000000033598
Abstract: Introduction: AS an uncommon neoplasm, goblet cell adenocarcinoma (GCA) is characterized by mixed endocrine-exocrine features. It is almost exclusively found in the appendix. Primary GCA of the anal canal is extremely rare. Case presentation: Herein… read more here.
Keywords: disease; anal canal; rare case; perianal paget ... See more keywords