Interactive Mechanisms of Supraspinal Sites of Opioid Analgesic Action: A Festschrift to Dr. Gavril W. Pasternak.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-020-00961-9
Abstract: Almost a half century of research has elaborated the discoveries of the central mechanisms governing the analgesic responses of opiates, including their receptors, endogenous peptides, genes and their putative spinal and supraspinal sites of action.… read more here.
Keywords: analgesic action; gavril pasternak; opioid analgesic; supraspinal sites ... See more keywords
The analgesic action of desmopressin in renal colic
Sign Up to like & getrecommendations! Published in 2018 at "Acta Clinica Belgica"
DOI: 10.1080/17843286.2017.1393160
Abstract: To the editor, We read the interesting article recently published by Kapila et al. entitled ‘The analgesic action of desmopressin in renal colic’ and wish to share our comments regarding their results [1]. According to… read more here.
Keywords: renal colic; analgesic action; effect; desmopressin renal ... See more keywords
Analgesic Action of Acetaminophen via Kv7 Channels
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010650
Abstract: The mechanism of acetaminophen (APAP) analgesia is at least partially unknown. Previously, we showed that the APAP metabolite N-acetyl-p-benzoquinone imine (NAPQI) activated Kv7 channels in neurons in vitro, and this activation of Kv7 channels dampened… read more here.
Keywords: kv7; effect; apap; kv7 channels ... See more keywords
Central dopaminergic system plays a role in the analgesic action of paracetamol: Preclinical evidence
Sign Up to like & getrecommendations! Published in 2017 at "Indian Journal of Pharmacology"
DOI: 10.4103/0253-7613.201029
Abstract: Objective: Even after 100 years of discovery, the exact mechanisms for the analgesic action of paracetamol are under scanner. It was recently proposed that paracetamol may act through different mechanisms, especially altering the serotoninergic system.… read more here.
Keywords: system; dopaminergic system; analgesic action; action paracetamol ... See more keywords