Centipede venom peptide SsmTX‐I with two intramolecular disulfide bonds shows analgesic activities in animal models
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DOI: 10.1002/psc.2988
Abstract: Pain is a major symptom of many diseases and results in enormous pressures on human body or society. Currently, clinically used analgesic drugs, including opioids and nonsteroidal anti‐inflammatory drugs, have adverse reactions, and thus, the… read more here.
Keywords: peptide; intramolecular disulfide; centipede venom; analgesic activities ... See more keywords
HR1405-01, a Safe intravenous NSAID with superior anti-inflammatory and analgesic activities in preclinical trials.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2022.114258
Abstract: Combinational utilization of intravenous non-steroidal anti-inflammatory drugs (NSAIDs) with opium analgesic is an effective alternative modality for pain control after surgery. This regimen is known for reducing the risk of addiction induced by opium analgesic.… read more here.
Keywords: inflammatory analgesic; hr1405 safe; analgesic activities; intravenous nsaid ... See more keywords
Chemical constituents, anti-inflammatory and analgesic activities of iridoids preparation from Phlomoides labiosa bunge
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DOI: 10.1080/14786419.2022.2104274
Abstract: Abstract This study reports the isolation of iridoids and cycloartane glycosides from the aerial parts of Phlomoides labiosa Bunge. Six compounds were isolated and the chemical structures were identified as phlorigidoside С (1), 8-O-acetylharpagide (2),… read more here.
Keywords: analgesic activities; phlomoides labiosa; sodium; labiosa bunge ... See more keywords
Secondary metabolites from Gentiana cruciata L. and their anti-inflammatory and analgesic activities.
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DOI: 10.1080/14786419.2022.2144301
Abstract: A previously unreported secoiridoid glycoside, cruciatoside (1) was isolated from the aerial parts of Gentiana cruciata L. along with ten known compounds eustomoside (2), eustomorusside (3), gentiopicroside (4), 6'-O-β-D-glucopyranosyl gentiopicroside (5), loganic acid (6), isoorientin… read more here.
Keywords: metabolites gentiana; analgesic activities; gentiana cruciata; anti inflammatory ... See more keywords
Antibacterial, anthelmintic, and analgesic activities of Piper sylvaticum (Roxb.) leaves and in silico molecular docking and PASS prediction studies of its isolated compounds
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Complementary and Integrative Medicine"
DOI: 10.1515/jcim-2018-0176
Abstract: Abstract Background In the present study, we investigated the antibacterial, anthelmintic, and analgesic activities of methanol extract of P. sylvaticum leaves (MEPSL) in experimental models. Then, computational analysis (in silico molecular docking and PASS prediction)… read more here.
Keywords: analgesic activities; pass; antibacterial anthelmintic; anthelmintic analgesic ... See more keywords