Calcium signaling mediated by aminergic GPCRs is impaired by the PI3K inhibitor LY294002 and its analog LY303511 in a PI3K-independent manner.
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DOI: 10.1016/j.ejphar.2020.173182
Abstract: The phosphoinositide 3-kinase (PI3K) inhibitor LY294002 (LY294) and its much less active analog LY303511 (LY303) constitute the paired probe that is commonly used to demonstrate the involvement of PI3K in intracellular signaling. We studied effects… read more here.
Keywords: pi3k inhibitor; inhibitor ly294002; analog ly303511; aminergic gpcrs ... See more keywords