Photoswitchable Inhibitors to Optically Control Specific Kinase Activity.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.3c00119
Abstract: Potent and selective small-molecule inhibitors are valuable tools to elucidate the functions of protein kinases within complex signaling networks. Incorporation of a photoswitchable moiety into the inhibitor scaffold offers the opportunity to steer inhibitor potency… read more here.
Keywords: optically control; kinase; inhibitors optically; analog sensitive ... See more keywords
Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14102285
Abstract: The human cytomegalovirus (HCMV) is a member of the beta-herpesvirus family and inflicts life-long latent infections in its hosts. HCMV has been shown to manipulate and dysregulate many cellular processes. One major interactor with the… read more here.
Keywords: pul97; kinase; analog sensitive; human cytomegalovirus ... See more keywords