Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents
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DOI: 10.3390/antibiotics10050489
Abstract: In the current work, in continuation of our recent research, we synthesized and studied new chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) and the membrane-penetrating cation triphenylphosphonium (TPP), which are linked by alkyl groups… read more here.
Keywords: analogs chloramphenicol; cam; cam tpp; dual acting ... See more keywords