Monocarbonyl Analogs of Curcumin Based on the Pseudopelletierine Scaffold: Synthesis and Anti-Inflammatory Activity
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222111384
Abstract: Curcumin (CUR) is a natural compound that exhibits anti-inflammatory, anti-bacterial, and other biological properties. However, its application as an effective drug is problematic due to its poor oral bioavailability, solubility in water, and poor absorption… read more here.
Keywords: anti inflammatory; pseudopelletierine; monocarbonyl analogs; curcumin based ... See more keywords
Quantitative structure activity relationship (qsar) study and biological evaluation on mono-ketone analogs of curcumin as antioxidant
Sign Up to like & getrecommendations! Published in 2020 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2020.00850.1
Abstract: The objective of this study was to design new mono-ketone analogs of curcumin and determine its lipid peroxidation inhibition. Molecular modeling studies were carried out by using the semi-empirical quantum chemical algorithm AM-1 method in… read more here.
Keywords: study; qsar; analogs curcumin; mono ketone ... See more keywords