Tideglusib and its analogs as inhibitors of Staphylococcus aureus SrtA.
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DOI: 10.1021/acs.jmedchem.0c00803
Abstract: Sortase A (SrtA) anchors surface proteins to the cell wall envelope, and it has attracted increasing interesting as a potential antivirulence target. Several small-molecule inhibitors for SrtA have been developed, but target validation remains largely… read more here.
Keywords: staphylococcus aureus; analogs inhibitors; srta tideglusib; inhibitors staphylococcus ... See more keywords