Discovery of an NAD+ analogue with enhanced specificity for PARP1
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DOI: 10.1039/d1sc06256e
Abstract: Among various protein posttranslational modifiers, poly-ADP-ribose polymerase 1 (PARP1) is a key player for regulating numerous cellular processes and events through enzymatic attachments of target proteins with ADP-ribose units donated by nicotinamide adenine dinucleotide (NAD+).… read more here.
Keywords: discovery nad; parp1; nad analogue; specificity ... See more keywords