Articles with "analogue structural" as a keyword



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A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

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Published in 2018 at "Molecules"

DOI: 10.3390/molecules23123381

Abstract: An in silico study has been conducted upon (3′RS,5′SR)-5-[2′-benzyl-5′-hydroxymethyl-1′,2′-isoxazolidin-3′-yl]uracil through a molecular dynamics/docking approach that highlights its potential inhibitory activity upon the wild-type pseudouridine 5′-monophosphate glycosidase. The crystal structure of this compound has been solved… read more here.

Keywords: pseudouridine; pseudouridine isoxazolidinyl; isoxazolidinyl nucleoside; approach ... See more keywords