Synthesis, characterization and biological evaluation of purine nucleoside analogues
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DOI: 10.1016/j.tetlet.2017.09.041
Abstract: We present a convenient route for the synthesis of C6-amino-C5’-N-cyclopropyl carboxamido-C2-alkynylated purine nucleoside analogues 11a-g via Sonogashira coupling reaction. The nine step synthesis is easy to perform, employing commercially available reagents. Compound 9 is used… read more here.
Keywords: purine nucleoside; characterization biological; biological evaluation; analogues 11a ... See more keywords