Combretastatin analogues in cancer biology: A prospective view
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29342
Abstract: The stilbenoid combretastatin and its derivatives are potent inhibitors of angiogenesis and cell proliferation and induce apoptosis. They disrupt cytoskeletal dynamics and modulate cell morphology, motility, and invasion. Hence they have been viewed as potential… read more here.
Keywords: combretastatin analogues; biology; cancer biology; combretastatin ... See more keywords
Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.05.017
Abstract: Andrographolide (AGP), a naturally occurring bioactive compound, has been investigated as a lead compound in cancer drug development. Its multidimensional therapeutic effects have raised interest among medicinal chemists, which has led to extensive structural modification… read more here.
Keywords: andrographolide analogues; developing andrographolide; challenges developing; advances challenges ... See more keywords