Articles with "analogues covalent" as a keyword



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Polygodial and Ophiobolin A Analogues for Covalent Crosslinking of Anticancer Targets

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222011256

Abstract: In a search of small molecules active against apoptosis-resistant cancer cells, including glioma, melanoma, and non-small cell lung cancer, we previously prepared α,β- and γ,δ-unsaturated ester analogues of polygodial and ophiobolin A, compounds capable of… read more here.

Keywords: analogues covalent; ophiobolin analogues; polygodial ophiobolin; cancer cells ... See more keywords