[Ln16] complexes (Ln = GdIII, DyIII): molecular analogues of natural minerals such as hydrotalcite.
Sign Up to like & getrecommendations! Published in 2018 at "Dalton transactions"
DOI: 10.1039/c8dt02609b
Abstract: Two new hexadecanuclear lanthanide complexes employing the 1,5-bis(salicylidene)carbohydrazide (H2bsc) ligand are reported herein. These polynuclear aggregates crystallize in the R3[combining macron] space group, which is unprecedented in a family of lanthanide complexes with such high… read more here.
Keywords: gdiii dyiii; ln16 complexes; molecular analogues; analogues natural ... See more keywords
Analogues of natural products yaequinolones as potential inflammatory inhibitors: Design, synthesis and biological evaluation.
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DOI: 10.2139/ssrn.4276528
Abstract: Inflammation is connected with a variety of diseases and there is still a need to develop more effective and safer anti-inflammatory drugs. Herein, we synthesized, resolved, and characterized eight enantiopure isomers of yaequinolone J1 (1),… read more here.
Keywords: yaequinolones potential; analogues natural; natural products; products yaequinolones ... See more keywords
Vasopressin and Its Analogues: From Natural Hormones to Multitasking Peptides
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DOI: 10.3390/ijms23063068
Abstract: Human neurohormone vasopressin (AVP) is synthesized in overlapping regions in the hypothalamus. It is mainly known for its vasoconstricting abilities, and it is responsible for the regulation of plasma osmolality by maintaining fluid homeostasis. Over… read more here.
Keywords: vasopressin analogues; avp analogues; hormones multitasking; analogues natural ... See more keywords
α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes
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DOI: 10.3390/ijms24065882
Abstract: In this study, α-ω-disubstituted polyamines exhibit a range of potentially useful biological activities, including antimicrobial and antibiotic potentiation properties. We have prepared an expanded set of diarylbis(thioureido)polyamines that vary in central polyamine core length, identifying… read more here.
Keywords: analogues natural; bacterial membranes; diacyl substituted; substituted analogues ... See more keywords
Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3
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DOI: 10.3390/metabo12020099
Abstract: Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and preliminary… read more here.
Keywords: natural chalcones; analogues natural; chalcones efficient; inhibitors akr1c3 ... See more keywords
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds
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DOI: 10.3390/ph15030339
Abstract: NAD+-dependent deacetylase SIRT1 regulates many different biological processes, thus being involved in pathogenic conditions such as metabolic diseases, neurogenerative disorders and cancer. Notably, experimental evidence underlined that the activation of SIRT1 had promising cardioprotective effects.… read more here.
Keywords: analogues natural; synthetic analogues; new synthetic; polyphenols sirtuin ... See more keywords