Conformationally Constrained Sialyl Analogues as New Potential Binders of h‐CD22
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DOI: 10.1002/cbic.202200076
Abstract: Here, two conformationally constrained sialyl analogues were synthesized and characterized in their interaction with the inhibitory Siglec, human CD22 (h‐CD22). An orthogonal approach, including biophysical assays (SPR and fluorescence), ligand‐based NMR techniques, and molecular modelling,… read more here.
Keywords: cd22; analogues new; conformationally constrained; sialyl analogues ... See more keywords