Articles with "analogues probe" as a keyword



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Galactosylsphingamides: new α-GalCer analogues to probe the F’-pocket of CD1d

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-04461-7

Abstract: Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for immune response modulation, as upon CD1d-mediated stimulation with KRN7000, a synthetic α-galactosylceramide, they produce a vast amount of cytokines. Here we present a synthesis that… read more here.

Keywords: analogues probe; cd1d; galactosylsphingamides new; probe pocket ... See more keywords