Evolutionary Analyses of Sequence and Structure Space Unravel the Structural Facets of SOD1
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DOI: 10.3390/biom9120826
Abstract: Superoxide dismutase (SOD) is the primary enzyme of the cellular antioxidant defense cascade. Misfolding, concomitant oligomerization, and higher order aggregation of human cytosolic SOD are linked to amyotrophic lateral sclerosis (ALS). Although, with two metal… read more here.
Keywords: analyses sequence; space; evolutionary analyses; sequence structure ... See more keywords