Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113130
Abstract: The development of biotherapeutic proteins requires the use of efficient analytical methods to support their manufacturing process and quality control (QC). Analytical approaches at intact and middle-up levels emerged as promising alternatives to bottom-up strategies… read more here.
Keywords: line; analysis; analysis automated; digestion ... See more keywords
High-throughput sample processing for methylation analysis in an automated, enclosed environment.
Sign Up to like & getrecommendations! Published in 2021 at "SLAS technology"
DOI: 10.1016/j.slast.2021.12.002
Abstract: Variation in methylcytosine is perhaps the most well-studied epigenetic mechanism of gene regulation. Methods that have been developed and implemented for assessing DNA methylation require sample DNA to be extracted, purified and chemically-processed through bisulfite… read more here.
Keywords: sample; sample processing; analysis automated; environment ... See more keywords
Continuous Partial Discharges Analysis During Automated Thermal Cycle Aging Experiment
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Energy Conversion"
DOI: 10.1109/tec.2020.3025434
Abstract: This work presents an experiment proposal for continuous partial discharge analysis during an automated thermal cycle experiment for hydro generator stator coils/bars. It is an innovative approach because we propose to perform partial discharges test… read more here.
Keywords: analysis automated; thermal cycle; continuous partial; partial discharges ... See more keywords
RadiomiX for Radiomics Analysis: Automated Approaches to Overcome Challenges in Replicability
Sign Up to like & getrecommendations! Published in 2025 at "Diagnostics"
DOI: 10.3390/diagnostics15151968
Abstract: Background/Objectives: To simplify the decision-making process in radiomics by employing RadiomiX, an algorithm designed to automatically identify the best model combination and validate them across multiple environments was developed, thus enhancing the reliability of results.… read more here.
Keywords: radiomics analysis; performance; auc; accuracy ... See more keywords