Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113130
Abstract: The development of biotherapeutic proteins requires the use of efficient analytical methods to support their manufacturing process and quality control (QC). Analytical approaches at intact and middle-up levels emerged as promising alternatives to bottom-up strategies… read more here.
Keywords: line; analysis; analysis automated; digestion ... See more keywords
High-throughput sample processing for methylation analysis in an automated, enclosed environment.
Sign Up to like & getrecommendations! Published in 2021 at "SLAS technology"
DOI: 10.1016/j.slast.2021.12.002
Abstract: Variation in methylcytosine is perhaps the most well-studied epigenetic mechanism of gene regulation. Methods that have been developed and implemented for assessing DNA methylation require sample DNA to be extracted, purified and chemically-processed through bisulfite… read more here.
Keywords: sample; sample processing; analysis automated; environment ... See more keywords
Continuous Partial Discharges Analysis During Automated Thermal Cycle Aging Experiment
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Energy Conversion"
DOI: 10.1109/tec.2020.3025434
Abstract: This work presents an experiment proposal for continuous partial discharge analysis during an automated thermal cycle experiment for hydro generator stator coils/bars. It is an innovative approach because we propose to perform partial discharges test… read more here.
Keywords: analysis automated; thermal cycle; continuous partial; partial discharges ... See more keywords