Identification of new IDH2R140Q inhibitors by discriminatory analysis‐based molecular docking and biological evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000063
Abstract: Isocitrate dehydrogenase 2 (IDH2) is a key enzyme in the regulation of cell metabolism. Its mutated type can lead to the accumulation of 2‐hydroxyglutarate, which is often related to malignancies such as acute myeloid leukemia.… read more here.
Keywords: new idh2r140q; analysis based; idh2r140q inhibitors; based molecular ... See more keywords
Interval analysis based robust truss optimization with continuous and discrete variables using mix-coded genetic algorithm
Sign Up to like & getrecommendations! Published in 2017 at "Structural and Multidisciplinary Optimization"
DOI: 10.1007/s00158-017-1668-6
Abstract: The problem of optimizing truss structures in the presence of uncertain parameters considering both continuous and discrete design variables is studied. An interval analysis based robust optimization method combined with the improved genetic algorithm is… read more here.
Keywords: interval analysis; analysis based; genetic algorithm; optimization ... See more keywords
Sensitivity analysis based multi-scale methods of coupled path-dependent problems
Sign Up to like & getrecommendations! Published in 2019 at "Computational Mechanics"
DOI: 10.1007/s00466-019-01762-8
Abstract: In the paper, a generalized essential boundary condition sensitivity analysis based implementation of $$\text {FE}^2$$ FE 2 and mesh-in-element (MIEL) multi-scale methods is derived as an alternative to standard implementations of multi-scale analysis, where the… read more here.
Keywords: analysis based; analysis; sensitivity analysis; multi scale ... See more keywords
Design, closed-form modeling and analysis of SU-8 based electrothermal microgripper for biomedical applications
Sign Up to like & getrecommendations! Published in 2019 at "Microsystem Technologies"
DOI: 10.1007/s00542-018-4059-z
Abstract: This paper presents design analysis of an SU-8 based 2-DoF electrothermal microgripper by developing a closed-form analytical model. The analytical model considers both the electro-thermal and thermo-mechanical domains and relates the applied actuation voltage to… read more here.
Keywords: design; analysis based; closed form; electrothermal microgripper ... See more keywords
An isogeometric analysis-based investigation of the flexocaloric effect in functionally graded dielectrics
Sign Up to like & getrecommendations! Published in 2021 at "Acta Mechanica"
DOI: 10.1007/s00707-021-03051-z
Abstract: The increasing obligatory demand for clean and environment-friendly alternates for refrigeration and air-conditioning has made solid-state refrigeration more alluring for researchers of the relevant fields. The flexocaloric effect is a mechanism providing solid-state refrigeration in… read more here.
Keywords: temperature; analysis based; functionally graded; flexocaloric effect ... See more keywords
Multiple beta spectrum analysis based on spectrum fitting
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-017-5409-5
Abstract: A method of separating beta spectra into each radionuclide spectrum was proposed in this study. Based on mathematical curve fits, the spectrum of each radionuclide was defined by using the maximum energy information and process… read more here.
Keywords: beta spectrum; analysis based; beta; multiple beta ... See more keywords
Spectral Analysis based on Wavelet Transform Maxima: Identification of Multi-order Stratigraphic Boundaries and Cycles
Sign Up to like & getrecommendations! Published in 2020 at "Mathematical Geosciences"
DOI: 10.1007/s11004-020-09879-w
Abstract: In sedimentology, stratigraphic sequences and cycles are ordered by time spans and physical scales, such as thickness, and bounded by discontinuities, including unconformities or flooding surfaces. Spectral analysis based on wavelet transform (WT) maxima is… read more here.
Keywords: order; analysis based; spectral analysis; maxima ... See more keywords
Isogeometric analysis based on geometric reconstruction models
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers of Mechanical Engineering"
DOI: 10.1007/s11465-021-0648-0
Abstract: In isogeometric analysis (IGA), the boundary representation of computer-aided design (CAD) and the tensor-product non-uniform rational B-spline structure make the analysis of three-dimensional (3D) problems with irregular geometries difficult. In this paper, an IGA method… read more here.
Keywords: based geometric; analysis based; analysis; isogeometric analysis ... See more keywords
Grey relational analysis-based genetic algorithm optimization of electrical discharge drilling of Nimonic-90 superalloy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Brazilian Society of Mechanical Sciences and Engineering"
DOI: 10.1007/s40430-018-1045-4
Abstract: Nickel-based superalloys are being increasingly used in aerospace, automotive industries due to their excellent thermo-mechanical properties. These applications require complex shapes and profiles which may not be obtained by conventional machining processes. These materials are… read more here.
Keywords: analysis based; relational analysis; electrical discharge; discharge drilling ... See more keywords
Overlapping Schwarz methods for isogeometric analysis based on generalized B-splines
Sign Up to like & getrecommendations! Published in 2020 at "Computer Methods in Applied Mechanics and Engineering"
DOI: 10.1016/j.cma.2020.113430
Abstract: Abstract Generalized B-splines (GB-splines) are a special class of Tchebycheff B-splines that are smooth piecewise function with sections in more general spaces. GB-splines allow for an exact representation of conic sections as well as transcendental… read more here.
Keywords: overlapping schwarz; schwarz methods; isogeometric analysis; generalized splines ... See more keywords
Dynamic response analysis-based fatigue evaluation of rib-to-deck welds considering welding residual stress
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Fatigue"
DOI: 10.1016/j.ijfatigue.2019.105249
Abstract: Abstract The coupling effects of welding residual stress (WRS), vehicle load and speed are investigated. The microhardness test was conducted to evaluate the WRS. The transient analysis-based model was developed to investigate the dynamic stress… read more here.
Keywords: dynamic response; residual stress; stress; analysis based ... See more keywords