Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1.
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DOI: 10.1093/nar/gkad416
Abstract: ANKLE1 is a nuclease that provides a final opportunity to process unresolved junctions in DNA that would otherwise create chromosomal linkages blocking cell division. It is a GIY-YIG nuclease. We have expressed an active domain… read more here.
Keywords: cleavage; analysis cleavage; mechanistic analysis; human ankle1 ... See more keywords