Retrospective single‐centre analysis of diagnostic approach to adult‐onset haemophagocytic lymphohistiocytosis
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DOI: 10.1111/imj.14891
Abstract: Haemophagocytic lymphohistiocytosis (HLH) is a rare disorder with a poor prognosis characterised by substantial immune activation leading to end‐organ failure. In childhood, genetic defects that impair cytotoxic function of natural killer cells and T cells.… read more here.
Keywords: analysis diagnostic; lymphohistiocytosis; centre analysis; retrospective single ... See more keywords
An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy
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DOI: 10.1182/bloodadvances.2025016978
Abstract: Key Points • Children with obesity frequently experience hepatotoxicity during ALL induction therapy.• Pretreatment lipid metabolites in the GPC pathway may identify patients at increased risk of hepatotoxicity. read more here.
Keywords: analysis diagnostic; diagnostic metabolomic; induction therapy; hepatotoxicity ... See more keywords