Analysis of drug interactions with serum proteins and related binding agents by affinity capillary electrophoresis: A review
Sign Up to like & getrecommendations! Published in 2022 at "Electrophoresis"
DOI: 10.1002/elps.202200191
Abstract: Biomolecules such as serum proteins can interact with drugs in the body and influence their pharmaceutical effects. Specific and precise methods that analyze these interactions are critical for drug development or monitoring and for diagnostic… read more here.
Keywords: affinity capillary; analysis drug; serum proteins; drug ... See more keywords
Analysis of drug residue in needle-exchange syringes in Washington, D.C.
Sign Up to like & getrecommendations! Published in 2021 at "Forensic science international"
DOI: 10.1016/j.forsciint.2021.111083
Abstract: For the first time in Washington, D.C., an analysis of drug residue from used needle-exchange syringes has been performed. This analysis is part of a larger initiative to understand the District of Columbia's illicit drug… read more here.
Keywords: drug residue; needle exchange; analysis; exchange syringes ... See more keywords
A systems-level analysis of drug–target–disease associations for drug repositioning
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in Functional Genomics"
DOI: 10.1093/bfgp/elx015
Abstract: Drug repositioning is the process of finding new therapeutic uses for existing, approved drugs-a process thathas value when considering the exorbitant costs of novel drug development. Several computational strategies exist as a way to predict… read more here.
Keywords: drug targets; level analysis; drug repositioning; drug ... See more keywords
Quantitative analysis of drug distribution in heterogeneous tissues using dual‐stacking capillary electrophoresis–mass spectrometry
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15988
Abstract: Intratumour heterogeneity frequently leads to drug resistance, which is a major issue in drug discovery. Drug distribution is one of the key factors for elucidating the resistance mechanism; however, quantitative and regional drug measurement is… read more here.
Keywords: heterogeneous tissues; analysis drug; quantitative analysis; drug distribution ... See more keywords
Analysis of drug adverse events in elderly patients based on the Japanese Adverse Drug Event Report Database
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13670
Abstract: Compared with the general adult population, pharmacokinetics and changes in drug responsiveness occur to a greater extent in the elderly. Interactions may occur between drugs used in combination to treat various diseases and may cause… read more here.
Keywords: drug adverse; analysis drug; elderly patients; patients based ... See more keywords
Analysis of drug repositioning and prediction techniques: A concise review.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220317164016
Abstract: High cost and risks are common issues in traditional drug research and development. Usually, it takes a long time to research and develop a drug, the effects of which are limited to relatively few targets.… read more here.
Keywords: repositioning prediction; analysis drug; drug repositioning; development ... See more keywords
Image smoothing using regularized entropy minimization and self-similarity for the quantitative analysis of drug diffusion
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_656_20
Abstract: Background: Targetable drug delivery is an important method for the treatment of liver tumors. For the quantitative analysis of drug diffusion, the establishment of a method for information collection and characterization of extracellular space is… read more here.
Keywords: drug; quantitative analysis; image; analysis drug ... See more keywords