Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids
Sign Up to like & getrecommendations! Published in 2020 at "Cell systems"
DOI: 10.1016/j.cels.2020.11.002
Abstract: SUMMARY Pluripotent stem cell (PSC)-derived organoids have emerged as novel multicellular models of human tissue development but display immature phenotypes, aberrant tissue fates, and a limited subset of cells. Here, we demonstrate that integrated analysis… read more here.
Keywords: liver organoids; cell; development; analysis engineering ... See more keywords
pyFoldX: enabling biomolecular analysis and engineering along structural ensembles.
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac072
Abstract: AVAILABILITY Recent years have seen an increase in the number of structures available, not only for new proteins but also for the same protein crystallized with different molecules and proteins. While protein design software have… read more here.
Keywords: analysis; analysis engineering; pyfoldx enabling; biomolecular analysis ... See more keywords