Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3′UTR binding
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DOI: 10.1038/s41598-020-68794-6
Abstract: Increasing evidence suggests that in Amyotrophic Lateral Sclerosis (ALS) mutated RNA binding proteins acquire aberrant functions, leading to altered RNA metabolism with significant impact on encoded protein levels. Here, by taking advantage of a human… read more here.
Keywords: cytoskeleton; mutant fus; fus; proteomics analysis ... See more keywords