Analysis of Gene Essentiality from TnSeq Data Using Transit.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1720-5_22
Abstract: TnSeq, or sequencing of transposon insertion libraries, has proven to be a valuable method for probing the functions of genes in a wide range of bacteria. TnSeq has found many applications for studying genes involved… read more here.
Keywords: analysis gene; transit; tnseq data; tnseq ... See more keywords
Meta-analysis of gene expression profiles in preeclampsia.
Sign Up to like & getrecommendations! Published in 2019 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2019.12.007
Abstract: OBJECTIVE Preeclampsia (PE) is a serious complication of pregnancy. It is considered a complex condition influenced by maternal genes, environmental factors and a deregulated immune response of the mother, but the etiology is largely unknown.… read more here.
Keywords: analysis gene; analysis; gene expression; meta analysis ... See more keywords
Mutational analysis of gene function in the Anaplasmataceae: Challenges and perspectives.
Sign Up to like & getrecommendations! Published in 2019 at "Ticks and tick-borne diseases"
DOI: 10.1016/j.ttbdis.2018.11.006
Abstract: Mutational analysis is an efficient approach to identifying microbial gene function. Until recently, lack of an effective tool for Anaplasmataceae yielding reproducible results has created an obstacle to functional genomics, because surrogate systems, e.g., ectopic… read more here.
Keywords: analysis; gene function; mutational analysis; analysis gene ... See more keywords
Analysis of Gene Expression Differences between Different Pancreatic Cells
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b02171
Abstract: The pancreas is a complex glandular organ in the abdominal cavity of humans. Pancreatic tissues contain different function regions that participate in different biological processes. Moreover, pancreatic cells can be clustered into different types according… read more here.
Keywords: expression differences; gene expression; pancreatic cells; analysis gene ... See more keywords
Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18585-3
Abstract: While both genes and environment contribute to phenotype, deciphering environmental contributions to phenotype is a challenge. Furthermore, elucidating how different phenotypes may share similar environmental etiologies also is challenging. One way to identify environmental influences… read more here.
Keywords: analysis gene; gene; seven phenotypes; gene expression ... See more keywords
Mutation analysis in the F8 gene in 485 families with haemophilia A and prenatal diagnosis in China
Sign Up to like & getrecommendations! Published in 2020 at "Haemophilia"
DOI: 10.1111/hae.14206
Abstract: Haemophilia A (HA) is an X‐linked bleeding disorder caused by mutations in the coagulation factor Ⅷ (F8) gene. Its incidence in men is estimated to be approximately 1/5000. read more here.
Keywords: families haemophilia; 485 families; mutation analysis; gene 485 ... See more keywords
Identification and Analysis of a Gene with Potential to Repress the IMD Pathway in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2019 at "Zoological Science"
DOI: 10.2108/zs190003
Abstract: The IMD pathway is one of the signal transduction pathways that regulates innate immune responses in Drosophila. To understand the regulation mechanism of the IMD pathway, we performed a mis-expression screening and identified a gene,… read more here.
Keywords: gene potential; imd pathway; identification analysis; analysis gene ... See more keywords
Towards quantitative analysis of gene regulation by enhancers.
Sign Up to like & getrecommendations! Published in 2017 at "Epigenomics"
DOI: 10.2217/epi-2017-0061
Abstract: Enhancers are regulatory DNA sequences that can activate transcription over large distances. Recent studies have revealed the widespread role of distant activation in eukaryotic gene regulation and in the development of various human diseases, including… read more here.
Keywords: gene regulation; quantitative analysis; towards quantitative; analysis gene ... See more keywords
Pan-Cancer Bioinformatics Analysis of Gene UBE2C
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.893358
Abstract: Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell… read more here.
Keywords: bioinformatics analysis; pan cancer; analysis gene; cancer bioinformatics ... See more keywords
Analysis of C3 Gene Variants in Patients With Idiopathic Recurrent Spontaneous Pregnancy Loss
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01813
Abstract: Miscarriage is the most common complication of pregnancy. Approximately 1% of couples trying to conceive will experience recurrent miscarriages, defined as three or more consecutive pregnancy losses and many of these cases remain idiopathic. Complement… read more here.
Keywords: pregnancy; gene variants; r1591g g1606d; analysis gene ... See more keywords
Analysis of Gene Single Nucleotide Polymorphisms in COVID-19 Disease Highlighting the Susceptibility and the Severity towards the Infection
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12112824
Abstract: Many factors may influence the risk of being infected by SARS-CoV-2, the coronavirus responsible for coronavirus disease 2019 (COVID-19). Exposure to the virus cannot explain the variety of an individual’s responses to the virus and… read more here.
Keywords: gene single; disease; nucleotide polymorphisms; single nucleotide ... See more keywords