Multi-marker analysis of genomic annotation on gastric cancer GWAS data from Chinese populations
Sign Up to like & getrecommendations! Published in 2018 at "Gastric Cancer"
DOI: 10.1007/s10120-018-0841-y
Abstract: BackgroundGastric cancer (GC) is one of the high-incidence and high-mortality cancers all over the world. Though genome-wide association studies (GWASs) have found some genetic loci related to GC, they could only explain a small fraction… read more here.
Keywords: genomic annotation; multi marker; analysis genomic; gwas data ... See more keywords
Integrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00991-w
Abstract: Hepatocellular carcinoma harbors numerous genomic and epigenomic aberrations of DNA copy numbers and DNA methylation. Transcriptomic deregulation by these aberrations plays key driver roles in heterogeneous progression of cancers. Here, we profile DNA copy numbers,… read more here.
Keywords: hepatocellular carcinoma; integrative analysis; genomic epigenomic; analysis genomic ... See more keywords
Proactive visual and statistical analysis of genomic data in Epiviz
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz883
Abstract: MOTIVATION Integrative analysis of genomic data that includes statistical methods in combination with visual exploration has gained widespread adoption. Many existing methods involve a combination of tools and resources: user interfaces that provide visualization of… read more here.
Keywords: proactive visual; data analysis; analysis; statistical analysis ... See more keywords
Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz027
Abstract: Abstract Oxidative DNA damage is a threat to genome stability. Using a genetic system in yeast that allows detection of mitotic recombination, we found that the frequency of crossovers is greatly elevated when cells are… read more here.
Keywords: oxidative dna; dna damage; analysis genomic;