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   Articles with "analysis identifies" as a keyword



Weighted correlation network analysis identifies multiple susceptibility loci for low‐grade glioma

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recommendations! Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.5368

Abstract: The current molecular classifications cannot completely explain the polarized malignant biological behavior of low‐grade gliomas (LGGs), especially for tumor recurrence. Therefore, we tried to identify suspicious hub genes related to tumor recurrence in LGGs. read more here.

Keywords: grade; analysis identifies; correlation network; network analysis ... See more keywords

Single‐Cell Transcriptomic Analysis Identifies a Novel OLR1 + SLC7A7 + Liver‐Enriched Metastatic Subset With Immunometabolic Rewiring in Pancreatic Cancer

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recommendations! Published in 2025 at "Cancer Medicine"

DOI: 10.1002/cam4.71345

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is an exceptionally lethal malignancy, with high percents of patients presenting with liver metastases (LM). However, the mechanisms driving liver metastases remain critical bottlenecks requiring urgent exploration. read more here.

Keywords: cancer; single cell; cell transcriptomic; analysis identifies ... See more keywords

In silico and functional analysis identifies key gene networks and novel gene candidates in obesity‐linked human visceral fat

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recommendations! Published in 2024 at "Obesity"

DOI: 10.1002/oby.24161

Abstract: Visceral adiposity is associated with increased proinflammatory activity, insulin resistance, diabetes risk, and mortality rate. Numerous individual genes have been associated with obesity, but studies investigating gene regulatory networks in human visceral obesity have been… read more here.

Keywords: functional analysis; silico functional; analysis identifies; human visceral ... See more keywords

Comparative proteomic analysis identifies differentially expressed proteins associated with meiotic arrest in cattle-yak hybrids.

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recommendations! Published in 2023 at "Proteomics"

DOI: 10.1002/pmic.202300107

Abstract: Cattle-yak, the interspecific hybrid between yak and taurine cattle, exhibits male-specific sterility. Massive loss of spermatogenic cells, especially spermatocytes, results in azoospermia in these animals. Currently, the mechanisms underlying meiosis block and defects in spermatocyte… read more here.

Keywords: cattle yak; comparative proteomic; proteins associated; analysis identifies ... See more keywords

Comprehensive pulmonary function analysis identifies predominant obstructive phenotype in former premature infants around one year of age

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recommendations! Published in 2024 at "Pediatric Pulmonology"

DOI: 10.1002/ppul.27287

Abstract: Preterm infants suffer from significant respiratory morbidity during the first years of life, but the underlying lung pathophysiology is not fully understood. This study aimed to comprehensively characterize the pulmonary functions of preterm infants using… read more here.

Keywords: comprehensive pulmonary; pulmonary function; function; analysis identifies ... See more keywords

Mutational analysis identifies functional Rap1, Su(Hw), and CTCF insulator sites in Arabidopsis thaliana.

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recommendations! Published in 2020 at "Plant cell reports"

DOI: 10.1007/s00299-020-02601-4

Abstract: KEY MESSAGE Genetic analysis identifies multiple, potential protein binding sites important for insulator function in Arabidopsis thaliana: Rap1 site in UASrpg, Su(Hw) site in UASrpg, and CTCF site in BEAD1c. Three non-plant insulators UASrpg, BEAD1c,… read more here.

Keywords: analysis identifies; arabidopsis thaliana; site; rap1 ... See more keywords
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Comprehensive transcriptomic analysis identifies novel regulators of lung adenocarcinoma

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recommendations! Published in 2020 at "Journal of Cell Communication and Signaling"

DOI: 10.1007/s12079-020-00565-4

Abstract: Lung adenocarcinoma (LA) is a subtype of lung cancer that accounts for about 40% of all lung cancers. Analysis of molecular mechanisms controlling this cancer can help scientists to detect, control and treat LA. Here,… read more here.

Keywords: lung adenocarcinoma; analysis identifies; transcriptomic analysis; comprehensive transcriptomic ... See more keywords
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A cross-species spatiotemporal proteomic analysis identifies UBE3A-dependent signaling pathways and targets

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recommendations! Published in 2022 at "Molecular Psychiatry"

DOI: 10.1038/s41380-022-01484-z

Abstract: Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A. Restoring UBE3A levels is a potential disease-modifying therapy for AS and has recently entered clinical trials. There is… read more here.

Keywords: analysis; spatiotemporal proteomic; species spatiotemporal; analysis identifies ... See more keywords
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Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

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recommendations! Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-02353-y

Abstract: Melanomas are well-known for their altered mRNA expression profiles. Yet, the specific contribution of mRNA binding proteins (mRBPs) to melanoma development remains unclear. Here we identify a cluster of melanoma-enriched genes under the control of… read more here.

Keywords: melanoma; analysis identifies; identifies melanoma; melanoma enriched ... See more keywords

Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML

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recommendations! Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-48953-3

Abstract: The overexpression of the ecotropic viral integration site-1 gene (EVI1/MECOM) marks the most lethal acute myeloid leukemia (AML) subgroup carrying chromosome 3q26 abnormalities. By taking advantage of the intersectionality of high-throughput cell-based and gene expression… read more here.

Keywords: proteogenomic analysis; orthogonal proteogenomic; identifies druggable; 3q26 aml ... See more keywords

Epigenome-wide Analysis Identifies Genes and Pathways Linked to Neurobehavioral Variation in Preterm Infants

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-42654-4

Abstract: Neonatal molecular biomarkers of neurobehavioral responses (measures of brain-behavior relationships), when combined with neurobehavioral performance measures, could lead to better predictions of long-term developmental outcomes. To this end, we examined whether variability in buccal cell… read more here.

Keywords: analysis identifies; age; wide analysis; preterm infants ... See more keywords