Analysis of the Localization of NLRs upon Shigella flexneri Infection Exemplified by NOD1.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1944-5_3
Abstract: NOD-like receptors (NLRs) are a family of pattern recognition receptors, able to respond to conserved microbial structures and endogenous danger signals. The NLR NOD1 responds to bacterial peptidoglycan, leading to recruitment of RIPK2, following activation… read more here.
Keywords: localization nlrs; shigella flexneri; infection; nlrs upon ... See more keywords
eQTL analysis from co-localization of 2739 GWAS loci detects associated genes across 14 human cancers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.10.059
Abstract: Genetic variants can predict other "linked" diseases because alterations in one or more genes in vivo may affect relevant phenotype properties. Our study systematically explored the pan-cancer common gene and cancer type-specific genes based on… read more here.
Keywords: cancer; eqtl analysis; analysis localization; gwas loci ... See more keywords