Molecular and functional analysis of monoclonal antibodies in support of biologics development
Sign Up to like & getrecommendations! Published in 2017 at "Protein & Cell"
DOI: 10.1007/s13238-017-0447-x
Abstract: Monoclonal antibody (mAb)-based therapeutics are playing an increasingly important role in the treatment or prevention of many important diseases such as cancers, autoimmune disorders, and infectious diseases. Multi-domain mAbs are far more complex than small… read more here.
Keywords: monoclonal antibodies; analysis; analysis monoclonal; molecular functional ... See more keywords
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection
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DOI: 10.1016/j.cell.2018.07.033
Abstract: Antibodies are promising post-exposure therapies against emerging viruses, but which antibody features and in vitro assays best forecast protection are unclear. Our international consortium systematically evaluated antibodies against Ebola virus (EBOV) using multidisciplinary assays. For each… read more here.
Keywords: protection; ebola virus; antibodies ebola; analysis monoclonal ... See more keywords
Genome analysis of the monoclonal marbled crayfish reveals genetic separation over a short evolutionary timescale
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DOI: 10.1038/s42003-020-01588-8
Abstract: The marbled crayfish ( Procambarus virginalis ) represents a very recently evolved parthenogenetic freshwater crayfish species that has invaded diverse habitats in Europe and in Madagascar. However, population genetic analyses have been hindered by the… read more here.
Keywords: marbled crayfish; analysis; analysis monoclonal; short evolutionary ... See more keywords
In-Silico Analysis of Monoclonal Antibodies against SARS-CoV-2 Omicron
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DOI: 10.3390/v14020390
Abstract: Omicron was designated by the WHO as a VOC on 26 November 2021, only 4 days after its sequence was first submitted. However, the impact of Omicron on current antibodies and vaccines remains unknown and… read more here.
Keywords: analysis monoclonal; rbd rbd; rbd; silico analysis ... See more keywords