Articles with "analysis osimertinib" as a keyword



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Population pharmacokinetic and pharmacodynamic analysis of osimertinib.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.e20536

Abstract: e20536Background: Osimertinib is an oral, potent, irreversible, CNS active EGFR-TKI, selective for sensitizing (EGFRm) and T790M resistance mutations, indicated for the treatment of patients with T... read more here.

Keywords: analysis osimertinib; pharmacodynamic analysis; population pharmacokinetic; pharmacokinetic pharmacodynamic ... See more keywords