Clinical Features and Genetic Analysis of Pediatric Patients with Alagille Syndrome Presenting Initially with Liver Function Abnormalities
Sign Up to like & getrecommendations! Published in 2018 at "Current Medical Science"
DOI: 10.1007/s11596-018-1879-0
Abstract: SummaryAlagille syndrome (AGS) is a multisystem disorder and caused by mutations in JAG1 or NOTCH2 gene. The diagnosis of AGS is hampered by its highly variable clinical manifestations. We performed a retrospective analysis on 16… read more here.
Keywords: clinical features; analysis; analysis pediatric; features genetic ... See more keywords
A Pragmatic Guide to Qualitative Analysis for Pediatric Researchers.
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DOI: 10.1093/jpepsy/jsac040
Abstract: OBJECTIVE To describe four approaches to qualitative analysis in order to provide a pragmatic, application-oriented guide to their use in research focused on children and their families. METHODS Four commonly used approaches to qualitative analysis-framework… read more here.
Keywords: analysis pediatric; analysis; approaches qualitative; pragmatic guide ... See more keywords
Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia
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DOI: 10.1182/bloodadvances.2021005381
Abstract: Key Points FLT3-ITD and high PRDM16 expression induced methylation changes at STAT5 and AP-1 binding sites in pediatric AML. Hypomethylated regions in PRDM16-highly expressed AMLs were correlated with enhanced chromatin accessibilities at multiple genomic regions. read more here.
Keywords: methylation; methylation analysis; genome wide; dna methylation ... See more keywords