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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7366-8_3
Abstract: Protein tunnels connecting the functional buried cavities with bulk solvent and protein channels, enabling the transport through biological membranes, represent the structural features that govern the exchange rates of ligands, ions, and water solvent. Tunnels…
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Keywords:
protein;
protein tunnels;
tunnels channels;
computational analysis ... See more keywords
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Published in 2023 at "ACS sensors"
DOI: 10.1021/acssensors.2c02148
Abstract: The profiling of the effector functions of single immune cells─including cytokine secretion─can lead to a deeper understanding of how the immune system operates and to potential diagnostics and therapeutical applications. Here, we report a microfluidic…
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Keywords:
secretion single;
secretion;
analysis protein;
single cells ... See more keywords
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Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03778e
Abstract: Protein termini are generally associated with protein stability. Taking advantage of charge state differences between terminal peptides and internal peptides, we developed a new method termed LysargiNase-assisted Analysis of the Protein N- and C-Terminome (NAPT)…
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Keywords:
terminome napt;
protein terminome;
analysis protein;
protein termini ... See more keywords
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Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20191661
Abstract: Abstract Tuberculosis (TB), a leading infectious disease caused by Mycobacterium tuberculosis strain, takes four human lives every minute globally. Paucity of knowledge on M. tuberculosis virulence and antibiotic resistance is the major challenge for tuberculosis…
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Keywords:
mycobacterium tuberculosis;
comprehensive analysis;
tuberculosis;
analysis protein ... See more keywords
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Published in 2021 at "Journal of Plant Interactions"
DOI: 10.1080/17429145.2020.1867770
Abstract: Smut, the most important sugarcane fungal disease in China, is caused by Sporisorium scitamineum. Smut infection causes severe cane and sugar yield loss. Whole-plant resistance response is characte...
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Keywords:
sporisorium scitamineum;
comparative analysis;
protein differential;
analysis protein ... See more keywords
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Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky358
Abstract: Abstract Despite significant advances in the understanding of protein structure-function relationships, revealing protein folding pathways still poses a challenge due to a limited number of relevant experimental tools. Widely-used experimental techniques, such as calorimetry or…
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Keywords:
analysis protein;
analysis;
web server;
calfitter web ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183548
Abstract: Lactobacillus paracasei SD1 is a potential probiotic strain due to its ability to survive several conditions in human dental cavities. To ascertain its safety for human use, we therefore performed a comprehensive bioinformatics analysis and…
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Keywords:
protein;
lactobacillus paracasei;
silico analysis;
paracasei sd1 ... See more keywords
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Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0265194
Abstract: Computational methods play a key role for investigating allosteric mechanisms in proteins, with the potential of generating valuable insights for innovative drug design. Here we present the SenseNet (“Structure ENSEmble NETworks”) framework for analysis of…
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Keywords:
protein structure;
analysis;
structure networks;
analysis protein ... See more keywords
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Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281530
Abstract: Early blight, caused by the necrotrophic fungus Alternaria solani, is an important foliar disease that causes major yield losses of potato. Effector proteins secreted by pathogens to host cells can inhibit host immune response to…
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Keywords:
identification functional;
protein secreted;
analysis protein;
alternaria solani ... See more keywords
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Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.700789
Abstract: The phylogenetic analysis of proteins conventionally relies on the evaluation of amino acid sequences or coding sequences. Individual amino acids have measurable features that allow the translation from strings of letters (amino acids or bases)…
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Keywords:
analysis protein;
analysis;
protein evolution;
quantitative analysis ... See more keywords
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Published in 2023 at "Applied Sciences"
DOI: 10.3390/app13116388
Abstract: The detection and analysis of protein complexes is essential for understanding the functional mechanism and cellular integrity. Recently, several techniques for detecting and analysing protein complexes from Protein–Protein Interaction (PPI) dataset have been developed. Most…
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Keywords:
protein complexes;
based weighted;
special structural;
analysis protein ... See more keywords