Transcriptome analysis provides critical answers to the “variants of uncertain significance” conundrum
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24394
Abstract: While whole‐genome and exome sequencing have transformed our collective understanding of genetics' role in disease pathogenesis, there are certain conditions and populations for whom DNA‐level data fails to identify the underlying genetic etiology. Specifically, patients… read more here.
Keywords: transcriptome analysis; uncertain significance; analysis; provides critical ... See more keywords
Multi-omics analysis provides insights into genetic architecture of flavonoid metabolites in Populus
Sign Up to like & getrecommendations! Published in 2021 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2021.113612
Abstract: Abstract Flavonoids are widely distributed secondary metabolites as well as a major class of chemical defenses in response to light intensity, temperature, and other external factors. However, systematic investigation on the genetic basis of flavonoids… read more here.
Keywords: omics analysis; insights genetic; analysis provides; geographical regions ... See more keywords
The Glomerulus Multiomics Analysis Provides Deeper Insights into Diabetic Nephropathy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00794
Abstract: Although diabetic nephropathy (DN) is the leading cause of the end-stage renal disease, the exact regulation mechanisms remain unknown. In this study, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven… read more here.
Keywords: multiomics analysis; deeper insights; glomerulus multiomics; analysis provides ... See more keywords
Corrigendum: Comparative phylogenomic analysis provides insights into TCP gene functions in Sorghum
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45801
Abstract: Scientific Reports 6: Article number: srep38488; published online: 05 December 2016; updated: 06 April 2017 The Acknowledgments section of this Article is incomplete, where: “R.S. and M.K.S. acknowledge the Ramalingaswami fellowship and grant from the… read more here.
Keywords: insights tcp; provides insights; analysis provides; corrigendum comparative ... See more keywords
Comparative genomic analysis provides insights into taxonomy and temperature adaption of Aeromonas salmonicida.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of fish diseases"
DOI: 10.1111/jfd.13767
Abstract: Aeromonas salmonicida has long been known as psychrophiles since it is mainly isolated from cold water fish, and recent reports have revealed the existence of mesophilic strains isolated from warm sources. However, the genetic differences… read more here.
Keywords: comparative genomic; adaption; genomic analysis; analysis provides ... See more keywords
Transcriptome analysis provides new insights into plants responses under phosphate starvation in association with chilling stress
Sign Up to like & getrecommendations! Published in 2022 at "BMC Plant Biology"
DOI: 10.1186/s12870-021-03381-z
Abstract: Background Chilling temperature reduces the rate of photosynthesis in plants, which is more pronounced in association with phosphate (Pi) starvation. Previous studies showed that Pi resupply improves recovery of the rate of photosynthesis in plants… read more here.
Keywords: analysis provides; phosphate starvation; transcriptome analysis; association ... See more keywords