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Published in 2020 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.14519
Abstract: Raltitrexed (RTX) is a thymidylate synthase inhibitor with large pharmacokinetics (PK) variability that can be administered in case of 5‐fluorouracil (5FU) intolerance or dihydropyrimidine dehydrogenase deficiency. While it is a more potent thymidylate synthase inhibitor…
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Keywords:
analysis raltitrexed;
exposure response;
response analysis;
assessing liver ... See more keywords