HS-SPME-GC-MS as an alternative method for NDMA analysis in ranitidine products.
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DOI: 10.1016/j.jpba.2020.113582
Abstract: N-nitrosodimethylamine (NDMA) is a carcinogenic contaminant that was accidentally discovered in drugs, such as valsartan and ranitidine, and more recently in metformin. Liquid chromatography tandem mass spectrometry (LC-MS/MS) is the method typically used for the… read more here.
Keywords: analysis ranitidine; ranitidine; analysis; method ... See more keywords