Clustering analysis revealed the autophagy classification and potential autophagy regulators' sensitivity of pancreatic cancer based on multi‐omics data
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4932
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy and is unresponsive to conventional therapeutic modalities due to its high heterogeneity, expounding the necessity, and priority of searching for effective biomarkers and drugs. Autophagy, as an… read more here.
Keywords: revealed autophagy; analysis revealed; clustering analysis; classification potential ... See more keywords
An in silico analysis revealed a novel evolutionary lineage of putative mitoviruses.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental microbiology"
DOI: 10.1111/1462-2920.16202
Abstract: Mitoviruses (family Mitoviridae) are small capsid-less RNA viruses that replicate in the mitochondria of fungi and plants. However, to date, the only authentic animal mitovirus infecting an insect was identified as Lutzomyia longipalpis mitovirus 1… read more here.
Keywords: novel evolutionary; putative mitoviruses; analysis revealed; lineage ... See more keywords
Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.14160
Abstract: Children with Down syndrome (DS) are at a 20‐fold increased risk for acute lymphoblastic leukemia (ALL). Compared to children with ALL and no DS (non‐DS‐ALL), those with DS and ALL (DS‐ALL) harbor uncommon genetic alterations,… read more here.
Keywords: epigenetic analysis; lymphoblastic leukemia; integrated genetic; acute lymphoblastic ... See more keywords
Diastolic Cardiomyopathy Secondary to Experimentally Induced Exacerbated Emphysema.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0382oc
Abstract: Chronic Obstructive Pulmonary Disease (COPD) is a clinical entity of increasing significance. COPD involves abnormalities of the airways and in emphysema, parenchymal pulmonary destruction. Cardiovascular disease has emerged as a significant comorbidity to COPD. Heart… read more here.
Keywords: copd; vivo; analysis revealed; diastolic cardiomyopathy ... See more keywords
Microstructural and chemical properties of gari and eba: Food products from cassava (Manihot esculenta Cranz)
Sign Up to like & getrecommendations! Published in 2021 at "Food Science and Technology International"
DOI: 10.1177/1082013221993607
Abstract: The microstructure, elemental distribution and rheological behavior of two varieties of gari and their doughs (eba) were investigated. SEM analysis revealed a concave structure with fibre-strands, which were altered after processing to eba. Gari nanostructures… read more here.
Keywords: food; analysis revealed; microstructural chemical; chemical properties ... See more keywords
Integrated genomic and transcriptomic analysis revealed mutation patterns of de-differentiated liposarcoma and leiomyosarcoma
Sign Up to like & getrecommendations! Published in 2020 at "BMC Cancer"
DOI: 10.1186/s12885-020-07456-2
Abstract: Background Treating patients with advanced sarcomas is challenging due to great histologic diversity among its subtypes. Leiomyosarcoma (LMS) and de-differentiated liposarcoma (DDLPS) are two common and aggressive subtypes of soft tissue sarcoma (STS). They differ… read more here.
Keywords: lms ddlps; fusion events; differentiated liposarcoma; analysis revealed ... See more keywords
Transcriptome analysis revealed the mechanism of Luciobarbus capito (L. capito) adapting high salinity: Antioxidant capacity, heat shock proteins, immunity.
Sign Up to like & getrecommendations! Published in 2023 at "Marine pollution bulletin"
DOI: 10.2139/ssrn.4384882
Abstract: Salinity has a significant influence on the physiology of freshwater aquatic organisms. However, there are few studies on the hematology and immunology of freshwater fish under high salinity. In the current study, we aimed to… read more here.
Keywords: signaling pathway; high salinity; analysis revealed; salinity ... See more keywords
Multi-omics analysis revealed the role of CCT2 in the induction of autophagy in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.967730
Abstract: Chaperonin containing TCP1 subunit 2 (CCT2) is essential in various neurodegenerative diseases, albeit its role in the pathogenesis of Alzheimer’s disease (AD) remains elusive. This study aimed to evaluate the role of CCT2 in Alzheimer’s… read more here.
Keywords: disease; alzheimer disease; role cct2; analysis revealed ... See more keywords
Integrative network analysis revealed the molecular function of folic acid on immunological enhancement in a sheep model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.913854
Abstract: We previously observed the beneficial role of folic acid supplemented from maternal or offspring diet on lamb growth performance and immunity. Twenty-four Hu lambs from four groups (mother received folic acid or not, offspring received… read more here.
Keywords: function folic; folic acid; muscle; analysis revealed ... See more keywords
Metabolomics Analysis Revealed the Characteristic Metabolites of Hemp Seeds Varieties and Metabolites Responsible for Antioxidant Properties
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.904163
Abstract: Hemp seeds are rich in metabolites such as protein, lipids and flavonoids, which are beneficial to health and can be used as a nutritional supplement. Few studies have focused on the metabolites of different hemp… read more here.
Keywords: hemp seeds; revealed characteristic; analysis revealed; responsible antioxidant ... See more keywords
Metabolomics Analysis Revealed Significant Metabolic Changes in Brain Cancer Cells Treated with Paclitaxel and/or Etoposide
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213940
Abstract: Cancer of the central nervous system (CNS) is ranked as the 19th most prevalent form of the disease in 2020. This study aims to identify candidate biomarkers and metabolic pathways affected by paclitaxel and etoposide,… read more here.
Keywords: cancer; cancer cells; analysis revealed; paclitaxel etoposide ... See more keywords