Challenges in next generation sequencing analysis of somatic mutations in transplant patients.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2018.04.119
Abstract: Analysis of somatic mutations in solid tumors and hematologic malignancies using targeted next generation sequencing (NGS)-based assays has become part of routine oncology practice as well as clinical trials. The use of paired tumor-normal DNA… read more here.
Keywords: next generation; generation sequencing; analysis somatic; somatic mutations ... See more keywords
Analysis of somatic microsatellite indels identifies driver events in human tumors
Sign Up to like & getrecommendations! Published in 2017 at "Nature Biotechnology"
DOI: 10.1038/nbt.3966
Abstract: Microsatellites (MSs) are tracts of variable-length repeats of short DNA motifs that exhibit high rates of mutation in the form of insertions or deletions (indels) of the repeated motif. Despite their prevalence, the contribution of… read more here.
Keywords: somatic microsatellite; microsatellite indels; human tumors; cancer ... See more keywords