Quantitative Single Cell Analysis for Transcriptional Activity of p53 Hetero-tetramers between Wild-type Protein and Oligomerization Domain
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DOI: 10.1246/cl.170980
Abstract: p53 acts as a transcriptional factor for tumor suppression via tetramerization. Although the dominant-negative effect occurs by hetero-oligomerization between wild-type and mutant p53, the precise mechanism remains unclear. Here, we report an analysis of the… read more here.
Keywords: hetero tetramers; analysis transcriptional; oligomerization; p53 ... See more keywords
Comparative Proteomic Analysis of Transcriptional and Regulatory Proteins Abundances in S. lividans and S. coelicolor Suggests a Link between Various Stresses and Antibiotic Production
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DOI: 10.3390/ijms232314792
Abstract: Streptomyces coelicolor and Streptomyces lividans constitute model strains to study the regulation of antibiotics biosynthesis in Streptomyces species since these closely related strains possess the same pathways directing the biosynthesis of various antibiotics but only… read more here.
Keywords: antibiotic production; transcriptional regulatory; regulatory proteins; analysis transcriptional ... See more keywords