Analysis of variants in GATA4 and FOG2/ZFPM2 demonstrates benign contribution to 46,XY disorders of sex development
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1095
Abstract: GATA‐binding protein 4 (GATA4) and Friend of GATA 2 protein (FOG2, also known as ZFPM2) form a heterodimer complex that has been shown to influence transcription of genes in a number of developmental systems. Recent… read more here.
Keywords: variants gata4; sex development; gata4 fog2; analysis variants ... See more keywords
Analysis of variants in mitochondrial genome and their putative pathogenicity in Tuberculosis patients from Mizoram, North east India.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.06.012
Abstract: Tuberculosis caused by Mycobacterium tuberculosis is one of the main global health concerns. In this study, the entire mitochondrial genome from blood samples of tuberculosis patients was analyzed to understand the possible mtDNA variants. The… read more here.
Keywords: tuberculosis patients; analysis variants; tuberculosis; variants mitochondrial ... See more keywords
Structural bioinformatics analysis of variants on GPCR function.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2019.04.007
Abstract: G protein-coupled receptors (GPCRs) are key membrane-embedded receptor proteins, with critical roles in cellular signal transduction. In the era of precision medicine, understanding the role of natural variants on GPCR function is critical, especially from… read more here.
Keywords: medicine; gpcr function; variants gpcr; analysis variants ... See more keywords