SIRT5 reduces the inflammatory response and barrier dysfunction in IL-17A-induced epidermal keratinocytes.
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DOI: 10.15586/aei.v51i1.675
Abstract: Psoriasis is a chronic multisystemic inflammatory disease with inflammatory cell infiltration, hyperproliferation of keratinocytes in skin lesions, and epidermal barrier dysfunction. Normal human epidermal keratinocytes (NHEKs) were stimulated with interleukin 17A (IL-17A). The expression levels… read more here.
Keywords: barrier dysfunction; dysfunction 17a; keratinocytes sirt5; dysfunction ... See more keywords