Cdc14 activation requires coordinated Cdk1-dependent phosphorylation of Net1 and PP2A–Cdc55 at anaphase onset
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DOI: 10.1007/s00018-019-03086-5
Abstract: Exit from mitosis and completion of cytokinesis require the inactivation of mitotic cyclin-dependent kinase (Cdk) activity. In budding yeast, Cdc14 phosphatase is a key mitotic regulator that is activated in anaphase to counteract Cdk activity.… read more here.
Keywords: cdc55; cdc14 activation; anaphase onset; activity ... See more keywords
Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onset
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DOI: 10.1371/journal.pgen.1007029
Abstract: Anaphase onset is an irreversible cell cycle transition that is triggered by the activation of the protease Separase. Separase cleaves the Mcd1 (also known as Scc1) subunit of Cohesin, a complex of proteins that physically… read more here.
Keywords: anaphase; separase; esp1; cohesin ... See more keywords