No clinically relevant hypersensitivity reactions in clinical trials with tralokinumab in asthma
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DOI: 10.1183/13993003.congress-2018.pa1034
Abstract: Introduction: Anaphylaxis and severe hypersensitivity reactions are a concern for any biologic substance. The anti-IL-13 agent tralokinumab is produced by a murine cell line and may thus incorporate immunogenic α-Gal epitopes in the Fab domain.… read more here.
Keywords: clinical studies; severe hypersensitivity; gal epitopes; hypersensitivity reactions ... See more keywords
Anaphylaxis and Severe Disseminated Intravascular Coagulation Due to Remdesivir
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DOI: 10.2169/internalmedicine.2994-23
Abstract: A 69-year-old woman suffering with multiple myeloma developed coronavirus disease 2019 (COVID-19). Shortly after administration of remdesivir, she presented with symptoms of facial flushing, wheezing, and hypoxemia. Subsequently, thrombocytopenia and hypofibrinogenemia rapidly manifested, leading to… read more here.
Keywords: anaphylaxis severe; disseminated intravascular; intravascular coagulation; remdesivir ... See more keywords
Emergency management of food-induced anaphylaxis and severe reactions in young infants.
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DOI: 10.2174/1573396319666221027115126
Abstract: read more here.
Keywords: induced anaphylaxis; anaphylaxis severe; food induced; management food ... See more keywords